pralsetinib [Ligand Id: 10033] activity data from GtoPdb

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  • kinase insert domain receptor in Human [GtoPdb: 1813] [UniProtKB: P35968]
Created with Highcharts 10.3.3ValuesChart context menukinase insert domain receptorpKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • ret proto-oncogene in Human [GtoPdb: 2185] [UniProtKB: P07949]
Created with Highcharts 10.3.3ValuesChart context menuret proto-oncogenepKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
kinase insert domain receptor in Human [GtoPdb: 1813] [UniProtKB: P35968]
GtoPdb In a biochemical assay. - 7.46 pIC50 35 nM IC50 Cancer Discov (2018) 8: 836-849 [PMID:29657135]
ret proto-oncogene in Human [GtoPdb: 2185] [UniProtKB: P07949]
GtoPdb In a biochemical assay. - 9.4 pIC50 0.4 nM IC50 Cancer Discov (2018) 8: 836-849 [PMID:29657135]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.