Top ▲

C-type lectin-like receptors (CLRs)

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

Click here for help

« Hide

C-type lectin-like receptors are single-pass type II membrane proteins involved widely in the recognition of pathogens and initiation of the innate response to maintain immune homeostasis [1-2].

Targets

Click here for help

Targets of relevance to immunopharmacology are highlighted in blue

DCIR (C-type lectin domain family 4 member A) Show summary » More detailed page go icon to follow link

BDCA2 (C-type lectin domain family 4 member C) Show summary » More detailed page go icon to follow link

DC-SIGN (CD209 molecule) Show summary » More detailed page go icon to follow link

Dectin-1 (C-type lectin domain family 7 member A) Show summary » More detailed page go icon to follow link

Dectin-2 (C-type lectin domain family 6 member A) Show summary » More detailed page go icon to follow link

Mincle (C-type lectin domain family 4 member E) Show summary » More detailed page go icon to follow link

C-type lectin domain family 12 member A / CD371 Show summary » More detailed page go icon to follow link

References

Click here for help

Show »

How to cite this family page

Database page citation:

C-type lectin-like receptors (CLRs). Accessed on 13/12/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=945.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Buneman OP, Faccenda E, Harding SD, Spedding M, Cidlowski JA, Fabbro D, Davenport AP, Striessnig J, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Introduction and Other Protein Targets. Br J Pharmacol. 180 Suppl 2:S1-22.