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Formylpeptide receptors C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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The formylpeptide receptors (nomenclature agreed by the NC-IUPHAR Subcommittee on the formylpeptide receptor family [26]) respond to exogenous ligands such as the bacterial product fMet-Leu-Phe (fMLP) and endogenous ligands such as annexin I (ANXA1, P04083) , cathepsin G (CTSG, P08311), amyloid β42, serum amyloid A and spinorphin, derived from β-haemoglobin (HBB, P68871).

Receptors

Targets of relevance to immunopharmacology are highlighted in blue

FPR1 C Show summary » More detailed page

FPR2/ALX C Show summary » More detailed page

FPR3 C Show summary » More detailed page

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Further reading

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References

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NC-IUPHAR subcommittee and family contributors

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How to cite this family page

Database page citation:

Richard D. Ye, Magnus Bäck, François Boulay, Nan Chiang, Sven-Erik Dahlén, Claes Dahlgren, Jeffrey Drazen, Jilly F. Evans, Craig Gerard, Philip M. Murphy, Marc Parmentier, Mark Quinn, G. Enrico Rovati, Charles N. Serhan, Takao Shimizu, Ji Ming Wang, Takehiko Yokomizo. Formylpeptide receptors. Accessed on 19/08/2019. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=23.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Christopoulos A, Davenport AP, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2017) The Concise Guide to PHARMACOLOGY 2017/18: G protein-coupled receptors. Br J Pharmacol. 174 Suppl 1: S17-S129.