Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	227	10p15.3	IDI2	isopentenyl-diphosphate delta isomerase 2	4
Mouse	-	227	13 A1	Idi2	isopentenyl-diphosphate delta isomerase 2
Rat	-	227	17q12.1	Idi2	isopentenyl-diphosphate delta isomerase 2

Previous and Unofficial Names

IPPI2 | isopentenyl-diphosphate delta isomerase 2 | IPP isomerase 2 | isopentenyl pyrophosphate isomerase 2

Database Links
Alphafold	Q9BXS1 (Hs), Q8BFZ6 (Mm)
BRENDA	5.3.3.2
Ensembl Gene	ENSG00000148377 (Hs), ENSMUSG00000033520 (Mm), ENSRNOG00000069625 (Rn)
Entrez Gene	91734 (Hs), 320581 (Mm), 502143 (Rn)
Human Protein Atlas	ENSG00000148377 (Hs)
KEGG Enzyme	5.3.3.2
KEGG Gene	hsa:91734 (Hs), mmu:320581 (Mm), rno:502143 (Rn)
OMIM	615389 (Hs)
Pharos	Q9BXS1 (Hs)
RefSeq Nucleotide	NM_033261 (Hs), NM_177197 (Mm), NM_001192008 (Rn)
RefSeq Protein	NP_150286 (Hs), NP_796171 (Mm), NP_001178937 (Rn)
UniProtKB	Q9BXS1 (Hs), Q8BFZ6 (Mm)
Wikipedia	IDI2 (Hs)

Selected 3D Structures
	Description:  Structure of Human Isopentenyl-diphosphate Delta-isomerase 2 PDB Id:  2PNY Resolution:  1.81Å Species:  Human References:

Enzyme Reaction
EC Number: 5.3.3.2 Isopentenyl diphosphate = dimethylallyl diphosphate

Cofactors
Cofactor Species Comments Reference Mg2+ Human Enzyme activity increases with increasing Mg2+ up to 20mM. 3,5 Mn2+ Human Activity increases up to a concentration of 100 micromolar Mn2+ then sharply decreases. 2-3

Tissue Distribution Comments

Highly expressed in skeletal muscle [1-2].