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Gene and Protein Information | ||||||
Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
Human | - | 702 | 19q13.2 | CEACAM5 | CEA cell adhesion molecule 5 |
Previous and Unofficial Names |
CEA | carcinoembryonic antigen-related cell adhesion molecule 5 | carcinoembryonic antigen related cell adhesion molecule 5 |
Database Links | |
Alphafold | P06731 (Hs) |
CATH/Gene3D | 2.60.40.10 |
ChEMBL Target | CHEMBL3712881 (Hs) |
Ensembl Gene | ENSG00000105388 (Hs) |
Entrez Gene | 1048 (Hs) |
Human Protein Atlas | ENSG00000105388 (Hs) |
KEGG Gene | hsa:1048 (Hs) |
OMIM | 114890 (Hs) |
Pharos | P06731 (Hs) |
RefSeq Nucleotide | NM_004363 (Hs) |
RefSeq Protein | NP_004354 (Hs) |
UniProtKB | P06731 (Hs) |
Wikipedia | CEACAM5 (Hs) |
Download all structure-activity data for this target as a CSV file
Antibodies | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Immunopharmacology Comments |
CD66e is included in GtoImmuPdb because of its role in pathogen recognition. |
Immuno Process Associations | ||
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General Comments |
CD66e (CEACAM5) is an epithelially expressed molecule required for cell adhesion, cellular migration, pathogen binding and activation of signaling pathways. This protein contains an immunoglobulin (Ig)-like domain that resembles the antibody variable domain, that has been coined the 'V-set domain'. The genes for all human V-set domain containing proteins are listed in HGNC gene group 590. |
CD molecules: CD66e (CEACAM5). Last modified on 07/08/2019. Accessed on 04/11/2024. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetoimmunopharmacology.org/GRAC/ObjectDisplayForward?objectId=2836.