bromodomain PHD finger transcription factor | Non-enzymatic BRD containing proteins | IUPHAR Guide to IMMUNOPHARMACOLOGY

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bromodomain PHD finger transcription factor

Target not currently curated in GtoImmuPdb

Target id: 2723

Nomenclature: bromodomain PHD finger transcription factor

Family: Non-enzymatic BRD containing proteins

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 2903 17q24 BPTF bromodomain PHD finger transcription factor
Mouse - 2921 11 E1 Bptf bromodomain PHD finger transcription factor
Rat - - 10q32.1 Bptf bromodomain PHD finger transcription factor
Previous and Unofficial Names
FAC1 | FALZ
Database Links
CATH/Gene3D
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
MS363 Hs Inhibition 5.8 pKi 1
pKi 5.8 (Ki 1.62x10-6 M) [1]

References

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1. Zhang G, Plotnikov AN, Rusinova E, Shen T, Morohashi K, Joshua J, Zeng L, Mujtaba S, Ohlmeyer M, Zhou MM. (2013) Structure-guided design of potent diazobenzene inhibitors for the BET bromodomains. J. Med. Chem., 56 (22): 9251-64. [PMID:24144283]

How to cite this page

Non-enzymatic BRD containing proteins: bromodomain PHD finger transcription factor. Last modified on 13/02/2017. Accessed on 19/09/2019. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetoimmunopharmacology.org/GRAC/ObjectDisplayForward?objectId=2723.