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Non-enzymatic BRD containing proteins C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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Bromodomains bind proteins with acetylated lysine residues, such as histones, to regulate gene transcription. Listed herein are examples of bromodomain-containing proteins for which sufficient pharmacology exists.

Targets

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Targets of relevance to immunopharmacology are highlighted in blue

bromodomain adjacent to zinc finger domain 1A Show summary » More detailed page go icon to follow link

bromodomain adjacent to zinc finger domain 1B Show summary » More detailed page go icon to follow link

bromodomain adjacent to zinc finger domain 2A C Show summary » More detailed page go icon to follow link

bromodomain adjacent to zinc finger domain 2B C Show summary » More detailed page go icon to follow link

bromodomain PHD finger transcription factor Show summary » More detailed page go icon to follow link

bromodomain testis associated Show summary » More detailed page go icon to follow link

bromodomain and PHD finger containing 1 Show summary » More detailed page go icon to follow link

bromodomain and PHD finger containing 3 Show summary » More detailed page go icon to follow link

bromodomain and WD repeat domain containing 1 Show summary » More detailed page go icon to follow link

bromodomain and WD repeat domain containing 3 Show summary » More detailed page go icon to follow link

CECR2 histone acetyl-lysine reader Show summary » More detailed page go icon to follow link

CREB binding protein C Show summary » More detailed page go icon to follow link

E1A binding protein p300 Show summary » More detailed page go icon to follow link

polybromo 1 C Show summary » More detailed page go icon to follow link

SMARCA2 (SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2) Show summary » More detailed page go icon to follow link

SMARCA4 (SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4) C Show summary » More detailed page go icon to follow link

pleckstrin homology domain interacting protein Show summary » More detailed page go icon to follow link

SP100 nuclear antigen Show summary » More detailed page go icon to follow link

SP110 nuclear body protein Show summary » More detailed page go icon to follow link

SP140 nuclear body protein Show summary » More detailed page go icon to follow link

SP140 nuclear body protein like Show summary » More detailed page go icon to follow link

zinc finger MYND-type containing 8 Show summary » More detailed page go icon to follow link

zinc finger MYND-type containing 11 Show summary » More detailed page go icon to follow link

tripartite motif containing 66 Show summary » More detailed page go icon to follow link

Further reading

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References

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How to cite this family page

Database page citation:

Non-enzymatic BRD containing proteins. Accessed on 03/12/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=867.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Buneman OP, Faccenda E, Harding SD, Spedding M, Cidlowski JA, Fabbro D, Davenport AP, Striessnig J, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Introduction and Other Protein Targets. Br J Pharmacol. 180 Suppl 2:S1-22.