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Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).
Bromodomains bind proteins with acetylated lysine residues, such as histones, to regulate gene transcription. Listed herein are examples of bromodomain-containing proteins for which sufficient pharmacology exists.
bromodomain adjacent to zinc finger domain 1A Show summary » More detailed page |
bromodomain adjacent to zinc finger domain 1B Show summary » More detailed page |
bromodomain adjacent to zinc finger domain 2A C Show summary » More detailed page |
bromodomain adjacent to zinc finger domain 2B C Show summary » More detailed page |
bromodomain PHD finger transcription factor Show summary » More detailed page |
bromodomain testis associated Show summary » More detailed page |
bromodomain and PHD finger containing 1 Show summary » More detailed page |
bromodomain and PHD finger containing 3 Show summary » More detailed page |
bromodomain and WD repeat domain containing 1 Show summary » More detailed page |
bromodomain and WD repeat domain containing 3 Show summary » More detailed page |
CECR2 histone acetyl-lysine reader Show summary » More detailed page |
CREB binding protein C Show summary » More detailed page |
E1A binding protein p300 Show summary » More detailed page |
polybromo 1 C Show summary » More detailed page |
SMARCA2 (SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2) Show summary » More detailed page |
SMARCA4 (SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4) C Show summary » More detailed page |
pleckstrin homology domain interacting protein Show summary » More detailed page |
SP100 nuclear antigen Show summary » More detailed page |
SP110 nuclear body protein Show summary » More detailed page |
SP140 nuclear body protein Show summary » More detailed page |
SP140 nuclear body protein like Show summary » More detailed page |
zinc finger MYND-type containing 8 Show summary » More detailed page |
zinc finger MYND-type containing 11 Show summary » More detailed page |
tripartite motif containing 66 Show summary » More detailed page |
Database page citation:
Non-enzymatic BRD containing proteins. Accessed on 03/12/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=867.
Concise Guide to PHARMACOLOGY citation:
Alexander SPH, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Buneman OP, Faccenda E, Harding SD, Spedding M, Cidlowski JA, Fabbro D, Davenport AP, Striessnig J, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Introduction and Other Protein Targets. Br J Pharmacol. 180 Suppl 2:S1-22.