Interleukin-12 receptor, β2 subunit | IL-12 receptor family | IUPHAR Guide to IMMUNOPHARMACOLOGY

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Interleukin-12 receptor, β2 subunit

  Target has curated data in GtoImmuPdb

Target id: 1716

Nomenclature: Interleukin-12 receptor, β2 subunit

Family: IL-12 receptor family

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

Quaternary Structure: Complexes
Interleukin-12 receptor
Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 862 01p31.3 IL12RB2 interleukin 12 receptor subunit beta 2
Mouse 1 874 Il12rb2 interleukin 12 receptor, beta 2
Rat - - Il12rb2 interleukin 12 receptor subunit beta 2
Previous and Unofficial Names
interleukin 12 receptor, beta 2 | Ifnm | interleukin 12 receptor
Database Links
Ensembl Gene
Entrez Gene
Human Protein Atlas
Immunopharmacology Comments
This protein is a subunit of the functional receptor heterodimer for the IL-12 cytokine.
Immuno Process Associations
Immuno Process:  Cytokine production & signalling
GO Annotations:  Associated to 6 GO processes
GO:0004896 cytokine receptor activity IBA
GO:0032729 positive regulation of interferon-gamma production IDA
GO:0034097 response to cytokine IMP
GO:0035722 interleukin-12-mediated signaling pathway TAS
GO:0070757 interleukin-35-mediated signaling pathway TAS
click arrow to show/hide IEA associations
GO:0032609 interferon-gamma production IEA

How to cite this page

IL-12 receptor family: Interleukin-12 receptor, β2 subunit. Last modified on 07/04/2017. Accessed on 14/07/2020. IUPHAR/BPS Guide to PHARMACOLOGY,