Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	1	819	8p11.22	ADAM9	ADAM metallopeptidase domain 9
Mouse	1	845	8 13.7 cM	Adam9	ADAM metallopeptidase domain 9
Rat	-	845	16q12.4	Adam9	ADAM metallopeptidase domain 9

Previous and Unofficial Names

cellular disintegrin-related protein | myeloma cell metalloproteinase | cone rod dystrophy 9 | disintegrin and metalloproteinase domain-containing protein 9 | CORD9 | MCMP | MDC9 | Mltng

Database Links
Specialist databases
MEROPS	M12.209 (Hs)
Other databases
Alphafold	Q13443 (Hs), Q61072 (Mm)
BRENDA	3.4.24.-
CATH/Gene3D	3.40.390.10, 4.10.70.10
ChEMBL Target	CHEMBL5982 (Hs)
Ensembl Gene	ENSG00000168615 (Hs), ENSMUSG00000031555 (Mm), ENSRNOG00000017231 (Rn)
Entrez Gene	8754 (Hs), 11502 (Mm), 290834 (Rn)
Human Protein Atlas	ENSG00000168615 (Hs)
KEGG Enzyme	3.4.24.-
KEGG Gene	hsa:8754 (Hs), mmu:11502 (Mm), rno:290834 (Rn)
OMIM	602713 (Hs)
Orphanet	ORPHA201516 (Hs)
Pharos	Q13443 (Hs)
RefSeq Nucleotide	NM_003816 (Hs), NM_007404 (Mm), NM_001014772 (Rn)
RefSeq Protein	NP_003807 (Hs), NP_031430 (Mm), NP_001014772 (Rn)
UniProtKB	Q13443 (Hs), Q61072 (Mm)
Wikipedia	ADAM9 (Hs)

Enzyme Reaction
EC Number: 3.4.24.-

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols	View all chemical structures	Click column headers to sort
Ligand Sp. Action Value Parameter Reference ilomastat Hs Inhibition 9.0 pIC50 1 ⤷ pIC50 9.0 (IC50 1x10-9 M) [1] Description: Measured in an in vitro assay.

Immuno Process Associations

Immuno Process:  Inflammation

Immuno Process:  Cytokine production & signalling

Immuno Process:  Cellular signalling

Clinically-Relevant Mutations and Pathophysiology
Disease:  Cone-rod dystrophy 9; CORD9 Synonyms: Cone rod dystrophy [Orphanet: ORPHA1872] [Disease Ontology: DOID:0050572] Disease Ontology: DOID:0050572 OMIM: 612775 Orphanet: ORPHA1872