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Methionyl aminopeptidase 1

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Target not currently curated in GtoImmuPdb

Target id: 1572

Nomenclature: Methionyl aminopeptidase 1

Family: M24: Methionyl aminopeptidase

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 386 4q23 METAP1 methionyl aminopeptidase 1
Mouse - 386 3 G3 Metap1 methionyl aminopeptidase 1
Rat - 386 2q44 Metap1 methionyl aminopeptidase 1
Previous and Unofficial Names Click here for help
MAP1A | Peptidase M | methionine aminopeptidase 1 | MetAP1A
Database Links Click here for help
Specialist databases
MEROPS M24.017 (Hs)
Other databases
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction Click here for help
EC Number:
EC Number:

Download all structure-activity data for this target as a CSV file go icon to follow link

Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
compound 14 [PMID: 23634668] Small molecule or natural product Primary target of this compound Hs Inhibition 7.0 pEC50 1
pEC50 7.0 (EC50 9.3x10-8 M) [1]
Description: In the presence of Co.


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1. Zhang F, Bhat S, Gabelli SB, Chen X, Miller MS, Nacev BA, Cheng YL, Meyers DJ, Tenney K, Shim JS et al.. (2013) Pyridinylquinazolines selectively inhibit human methionine aminopeptidase-1 in cells. J Med Chem, 56 (10): 3996-4016. [PMID:23634668]

How to cite this page

M24: Methionyl aminopeptidase: Methionyl aminopeptidase 1. Last modified on 14/07/2015. Accessed on 02/12/2022. IUPHAR/BPS Guide to PHARMACOLOGY,