Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	386	4q23	METAP1	methionyl aminopeptidase 1
Mouse	-	386	3 G3	Metap1	methionyl aminopeptidase 1
Rat	-	386	2q44	Metap1	methionyl aminopeptidase 1

Previous and Unofficial Names

MAP1A | Peptidase M | methionine aminopeptidase 1 | MetAP1A

Database Links
Specialist databases
MEROPS	M24.017 (Hs)
Other databases
Alphafold	P53582 (Hs), Q8BP48 (Mm), D3ZE72 (Rn)
BRENDA	3.4.11.3, 3.4.11.18
ChEMBL Target	CHEMBL2474 (Hs)
Ensembl Gene	ENSG00000164024 (Hs), ENSMUSG00000005813 (Mm), ENSRNOG00000012947 (Rn)
Entrez Gene	23173 (Hs), 75624 (Mm), 295500 (Rn)
Human Protein Atlas	ENSG00000164024 (Hs)
KEGG Enzyme	3.4.11.3, 3.4.11.18
KEGG Gene	hsa:23173 (Hs), mmu:75624 (Mm), rno:295500 (Rn)
OMIM	610151 (Hs)
Pharos	P53582 (Hs)
RefSeq Nucleotide	NM_015143 (Hs), NM_175224 (Mm), NM_001106476 (Rn)
RefSeq Protein	NP_055958 (Hs), NP_780433 (Mm), NP_001099946 (Rn)
UniProtKB	P53582 (Hs), Q8BP48 (Mm), D3ZE72 (Rn)
Wikipedia	METAP1 (Hs)

Enzyme Reaction
EC Number: 3.4.11.3 EC Number: 3.4.11.18

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols	View all chemical structures	Click column headers to sort
Ligand Sp. Action Value Parameter Reference compound 14 [PMID: 23634668] Hs Inhibition 7.0 pEC50 1 ⤷ pEC50 7.0 (EC50 9.3x10-8 M) [1] Description: In the presence of Co.