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Glutamyl aminopeptidase

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Target not currently curated in GtoImmuPdb

Target id: 1568

Nomenclature: Glutamyl aminopeptidase

Family: M1: Aminopeptidase N

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 957 4q25 ENPEP glutamyl aminopeptidase
Mouse 1 945 3 57.92 cM Enpep glutamyl aminopeptidase
Rat 1 945 2q42 Enpep glutamyl aminopeptidase
Previous and Unofficial Names Click here for help
differentiation antigen gp160 | EAP | APA | Ly51 | CD249 | gp160 | glutamyl aminopeptidase (aminopeptidase A)
Database Links Click here for help
Specialist databases
MEROPS M01.003 (Hs)
Other databases
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction Click here for help
EC Number:

Download all structure-activity data for this target as a CSV file go icon to follow link

Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
compound 40 [PMID: 10602705] Small molecule or natural product Primary target of this compound Mm Inhibition 9.1 pKi 1
pKi 9.1 (Ki 8.73x10-10 M) [1]


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1. David C, Bischoff L, Meudal H, Mothé A, De Mota N, DaNascimento S, Llorens-Cortes C, Fournié-Zaluski MC, Roques BP. (1999) Investigation of subsite preferences in aminopeptidase A (EC led to the design of the first highly potent and selective inhibitors of this enzyme. J Med Chem, 42 (25): 5197-211. [PMID:10602705]

How to cite this page

M1: Aminopeptidase N: Glutamyl aminopeptidase. Last modified on 22/07/2015. Accessed on 11/12/2023. IUPHAR/BPS Guide to PHARMACOLOGY,