fMet-Ile-Val-Thr-Leu-Phe   Click here for help

GtoPdb Ligand ID: 5841

Synonyms: fMet-Ile-Val-Thr-Leu-Phe [L. monocytogenes]
Compound class: Peptide or derivative
Comment: From the bacterium L. monocytogenes
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
References
1. He HQ, Liao D, Wang ZG, Wang ZL, Zhou HC, Wang MW, Ye RD. (2013)
Functional characterization of three mouse formyl peptide receptors.
Mol Pharmacol, 83 (2): 389-98. [PMID:23160941]
2. Rabiet MJ, Huet E, Boulay F. (2005)
Human mitochondria-derived N-formylated peptides are novel agonists equally active on FPR and FPRL1, while Listeria monocytogenes-derived peptides preferentially activate FPR.
Eur J Immunol, 35 (8): 2486-95. [PMID:16025565]
3. Southgate EL, He RL, Gao JL, Murphy PM, Nanamori M, Ye RD. (2008)
Identification of formyl peptides from Listeria monocytogenes and Staphylococcus aureus as potent chemoattractants for mouse neutrophils.
J Immunol, 181 (2): 1429-37. [PMID:18606697]