Compound class:
Metabolite or derivative
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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References |
1. Maciver B, Smith CP, Hill WG, Zeidel ML. (2008)
Functional characterization of mouse urea transporters UT-A2 and UT-A3 expressed in purified Xenopus laevis oocyte plasma membranes. Am J Physiol Renal Physiol, 294 (4): F956-64. [PMID:18256317] |
2. Nawata CM, Dantzler WH, Pannabecker TL. (2015)
Alternative channels for urea in the inner medulla of the rat kidney. Am J Physiol Renal Physiol, 309 (11): F916-24. [PMID:26423860] |
3. Zhao D, Sonawane ND, Levin MH, Yang B. (2007)
Comparative transport efficiencies of urea analogues through urea transporter UT-B. Biochim Biophys Acta, 1768 (7): 1815-21. [PMID:17506977] |