Abbreviated name: DHEA
Synonyms: androstenolone | dehydroepiandrostenedione | DHA | Intrarosa® | Prasterone
dehydroepiandrosterone is an approved drug (FDA (2016), EMA (2018))
Compound class:
Metabolite
Comment: Dehydroepiandrosterone (DHEA; prasterone) is a precursor that is converted to oestrogens and androgens.
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References |
1. Maksay G, Laube B, Betz H. (2001)
Subunit-specific modulation of glycine receptors by neurosteroids. Neuropharmacology, 41 (3): 369-76. [PMID:11522328] |
2. Rose KA, Stapleton G, Dott K, Kieny MP, Best R, Schwarz M, Russell DW, Björkhem I, Seckl J, Lathe R. (1997)
Cyp7b, a novel brain cytochrome P450, catalyzes the synthesis of neurosteroids 7alpha-hydroxy dehydroepiandrosterone and 7alpha-hydroxy pregnenolone. Proc Natl Acad Sci USA, 94 (10): 4925-30. [PMID:9144166] |