[3H]-IPP   Click here for help

GtoPdb Ligand ID: 11368

 Ligand is labelled  Ligand is radioactive
Compound class: Peptide
Comment: A radiolabelled analogue of the food-derived tripeptide Ile-Pro-Pro, that was use to demonstrate PEPT1-mediated transport of IPP across the small intestinal epithelium [1-2].
References
1. Gleeson JP, Brayden DJ, Ryan SM. (2017)
Evaluation of PepT1 transport of food-derived antihypertensive peptides, Ile-Pro-Pro and Leu-Lys-Pro using in vitro, ex vivo and in vivo transport models.
Eur J Pharm Biopharm, 115: 276-284. [PMID:28315445]
2. Gleeson JP, Frías JM, Ryan SM, Brayden DJ. (2018)
Sodium caprate enables the blood pressure-lowering effect of Ile-Pro-Pro and Leu-Lys-Pro in spontaneously hypertensive rats by indirectly overcoming PepT1 inhibition.
Eur J Pharm Biopharm, 128: 179-187. [PMID:29684535]