t-Boc-FLFLF   Click here for help

GtoPdb Ligand ID: 1030

Compound class: Peptide
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1. Freer RJ, Day AR, Muthukumaraswamy N, Pinon D, Wu A, Showell HJ, Becker EL. (1982)
Formyl peptide chemoattractants: a model of the receptor on rabbit neutrophils.
Biochemistry, 21 (2): 257-63. [PMID:6280748]
2. Stenfeldt AL, Karlsson J, Wennerås C, Bylund J, Fu H, Dahlgren C. (2007)
Cyclosporin H, Boc-MLF and Boc-FLFLF are antagonists that preferentially inhibit activity triggered through the formyl peptide receptor.
Inflammation, 30 (6): 224-9. [PMID:17687636]
3. Walther A, Riehemann K, Gerke V. (2000)
A novel ligand of the formyl peptide receptor: annexin I regulates neutrophil extravasation by interacting with the FPR.
Mol Cell, 5 (5): 831-40. [PMID:10882119]
4. Wenzel-Seifert K, Grünbaum L, Seifert R. (1991)
Differential inhibition of human neutrophil activation by cyclosporins A, D, and H. Cyclosporin H is a potent and effective inhibitor of formyl peptide-induced superoxide formation.
J Immunol, 147 (6): 1940-6. [PMID:1653806]
5. Wenzel-Seifert K, Seifert R. (1993)
Cyclosporin H is a potent and selective formyl peptide receptor antagonist. Comparison with N-t-butoxycarbonyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L- leucyl-L-phenylalanine and cyclosporins A, B, C, D, and E.
J Immunol, 150 (10): 4591-9. [PMID:8387097]