[des-Arg10]icatibant   Click here for help

GtoPdb Ligand ID: 663

Synonyms: [D-Arg-[Hyp3,Thi5,D-Tic7,Oic8]-des-Arg9]bradykinin | [des-Arg10]HOE140
Comment: Synthetic analogue of bradykinin
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Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
B1 receptor Mm Antagonist Antagonist 7.2 pA2 - 4
pA2 7.2 [4]
B1 receptor Mm Antagonist Antagonist 7.6 pKi - 2
pKi 7.6 [2]
B1 receptor Hs Antagonist Antagonist 6.6 – 8.4 pKi - 1,3
pKi 6.6 – 8.4 [1,3]
B1 receptor Rn Antagonist Antagonist 7.4 – 7.6 pKi - 3
pKi 7.4 – 7.6 [3]