DkTx   Click here for help

GtoPdb Ligand ID: 4178

Synonyms: Double-knot toxin
Comment: Toxin from Chilobrachys guangxiensis (Chinese earth tiger tarantula). Analysis of the mechanism of TRPV1 activation by DkTx is reported by Geron et al. [2].
Click here for help
Selectivity at ion channels
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
TRPV1 Rn Activator Activation 6.6 pEC50 - 1
pEC50 6.6 (EC50 2.3x10-10 M) [1]
Voltage: Physiological