Cs+   

GtoPdb Ligand ID: 2356

Synonyms: cesium cation | cesium ion
Compound class: Inorganic
Selectivity at ion channels
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
Kir4.1 Rn Channel blocker Antagonist - - 3x10-5 - 3x10-4 15
Conc range: 3x10-5 - 3x10-4 M [15]
Voltage: -160.0 – 50.0 mV
Kir4.2 Mm Channel blocker Antagonist - - 1x10-5 - 1x10-4 12
Conc range: 1x10-5 - 1x10-4 M Kir4.2 expressed in Xenopus oocytes [12]
Voltage: -120.0 – 100.0 mV
Kir2.2 Mm Gating inhibitor Antagonist - - 5x10-6 - 5x10-5 14
Conc range: 5x10-6 - 5x10-5 M [14]
Voltage: -150.0 – -50.0 mV
Kir2.4 Hs Channel blocker Antagonist 3.0 – 4.1 pKd - 5
pKd 3.0 – 4.1 [5]
Voltage: -60.0 – -100.0 mV
Kir2.1 Mm Channel blocker Antagonist 1.3 – 4.0 pKd 3x10-5 - 3x10-4 1
pKd 1.3 – 4.0 Conc range: 3x10-5 - 3x10-4 M [1]
Voltage: 0.0 – -102.0 mV
Kv12.2 Hs Channel blocker Pore blocker 1.2 pKd - 2
pKd 1.2 [2]
Kir2.3 Hs Channel blocker Antagonist 1.3 – 4.5 pKi 3x10-6 - 3x10-4 9
pKi 1.3 – 4.5 Conc range: 3x10-6 - 3x10-4 M [9]
Voltage: 0.0 – -130.0 mV
Kir2.4 Rn Channel blocker Antagonist 2.1 pKi - 16
pKi 2.1 [16]
Voltage: -80.0 mV
Kir7.1 Hs Channel blocker Antagonist 1.6 pKi - 4,7,11
pKi 1.6 [4,7,11]
Voltage: -100.0 mV
Kir3.4 Rn Channel blocker Antagonist 4.0 pEC50 - 6
pEC50 4.0 [6]
Voltage: -80.0 mV
Kir2.3 Mm Channel blocker Antagonist 5.0 pIC50 5x10-6 - 5x10-4 8,10
pIC50 5.0 Conc range: 5x10-6 - 5x10-4 M [8,10]
Voltage: -150.0 mV
HCN3 Hs Channel blocker Antagonist 3.8 pIC50 - 13
pIC50 3.8 (IC50 1.57x10-4 M) [13]
Voltage: -40.0 mV
HCN4 Hs Channel blocker Antagonist 3.8 pIC50 - 13
pIC50 3.8 (IC50 1.75x10-7 M) [13]
Voltage: -40.0 mV
HCN1 Hs Channel blocker Antagonist 3.7 pIC50 - 13
pIC50 3.7 (IC50 2.01x10-7 M) [13]
Voltage: -40.0 mV
HCN2 Hs Channel blocker Antagonist 3.7 pIC50 - 13
pIC50 3.7 (IC50 2.06x10-7 M) [13]
Voltage: -40.0 mV
Kir1.1 Rn Channel blocker Antagonist 2.9 pIC50 - 17
pIC50 2.9 [17]
Voltage: -120.0 mV
Kir5.1 Rn Channel blocker Antagonist - - - 3
[3]
Voltage: Physiological