naratuximab emtansine   Click here for help

GtoPdb Ligand ID: 9949

Synonyms: IMGN-529 | IMGN529 | K7153A-SMCC-DM1
Immunopharmacology Ligand
Compound class: Antibody
Comment: Naratuximab emtansine (IMGN529) is a CD37- targeting antibody drug conjugate carrying a potent anti-mitotic agent (maytansinoid DM1) payload. This ADC is being investigated for clinical efficacy as a treatment for B cell malignancies, with empahsis on diffuse large B cell lymphoma (DLBCL) in light of preliminary results from the phase 1 clinical trial NCT01534715 [4].
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Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
10238 naratuximab emtansine
Synonyms Click here for help
IMGN-529 | IMGN529 | K7153A-SMCC-DM1
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 602
Other databases
GtoPdb PubChem SID 374883836
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