cevimeline   Click here for help

GtoPdb Ligand ID: 9658

Synonyms: Evoxac®
Approved drug
cevimeline is an approved drug (FDA (2000))
Compound class: Synthetic organic
Comment: Cevimeline is an orally administered cholinergic analogue with parasympathomimetic activity. The INN is a mixture of enantiomers. We show the structure without stereochemistry to represent the mixture.
Click here for help
IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: cevimeline

2D Structure
Click here for help
Click here for structure editor
Physico-chemical Properties
Click here for help
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 0
Topological polar surface area 37.77
Molecular weight 199.1
XLogP 1.29
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
Click here for help
Canonical SMILES CC1SCC2(O1)CN1CCC2CC1
Isomeric SMILES CC1SCC2(O1)CN1CCC2CC1
InChI InChI=1S/C10H17NOS/c1-8-12-10(7-13-8)6-11-4-2-9(10)3-5-11/h8-9H,2-7H2,1H3
InChI Key WUTYZMFRCNBCHQ-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (2000))
International Nonproprietary Names Click here for help
INN number INN
7540 cevimeline
Synonyms Click here for help
Evoxac®
Database Links Click here for help
Specialist databases
GPCRdb Ligand cevimeline
Other databases
CAS Registry No. 107233-08-9 (source: WHO INN record)
ChEMBL Ligand CHEMBL168815
DrugCentral Ligand 584
GtoPdb PubChem SID 348353617
PubChem CID 2684
Search Google for chemical match using the InChIKey WUTYZMFRCNBCHQ-UHFFFAOYSA-N
Search Google for chemicals with the same backbone WUTYZMFRCNBCHQ
Search PubMed clinical trials cevimeline
Search PubMed titles cevimeline
Search PubMed titles/abstracts cevimeline
UniChem Compound Search for chemical match using the InChIKey WUTYZMFRCNBCHQ-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey WUTYZMFRCNBCHQ-UHFFFAOYSA-N