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clazakizumab   Click here for help

GtoPdb Ligand ID: 9195

Synonyms: ALD-518 | ALD518 | BMS-945429
Immunopharmacology Ligand
Compound class: Antibody
Comment: Clazakizumab is an investigational, aglycosylated, humanized (from a rabbit parental antibody) monoclonal antibody targeting interleukin-6, with anti-inflammatory potential [2].
Peptide sequence and structural information for this antibody are available from its IMGT/mAb-db record. BLAST peptide sequence analysis reveals identical matches with peptides claimed in patent US8062864 [3]. Results presented in the patent show that the preferred antibodies block interaction of IL-6 with the IL-6 receptor, but no precise binding affinity data is provided.
Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
9599 clazakizumab
Synonyms Click here for help
ALD-518 | ALD518 | BMS-945429
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 414
Other databases
GtoPdb PubChem SID 315661274
Search PubMed clinical trials clazakizumab
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Wikipedia Clazakizumab