corticotrophin-releasing hormone   Click here for help

GtoPdb Ligand ID: 912

Synonyms: CRF
Compound class: Endogenous peptide in human, mouse or rat
Species: Human, Mouse, Rat
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species

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View more information in the IUPHAR Pharmacology Education Project: crh

Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Neuropeptides
Synonyms Click here for help
CRF
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
CRH corticotropin releasing hormone Human prepro-corticotropin releasing hormone corticoliberin, corticotropin-releasing factor, CRF
Crh corticotropin releasing hormone Mouse prepro-corticotropin releasing hormone corticotropin releasing factor, corticotropin-releasing factor, CRF, LOC383938
Crh corticotropin releasing hormone Rat prepro-corticotropin releasing hormones corticoliberin, corticotropin-releasing factor, corticotropin releasing hormone, corticotropin-releasing hormone, CRF
Database Links Click here for help
Specialist databases
GPCRdb Ligand corticotrophin-releasing hormone
Other databases
Ensembl Gene ENSMUSG0000004979 (Mm), ENSRNOG00000012703 (Rn), ENSG00000147571 (Hs)
Entrez Gene 81648 (Rn), 1392 (Hs), 12918 (Mm)
GtoPdb PubChem SID 135651696
Human Protein Atlas ENSG00000147571 (Hs)
UniProtKB P01143 (Rn), Q8CIT0 (Mm), P06850 (Hs)
Wikipedia Corticoliberin