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fulranumab   Click here for help

GtoPdb Ligand ID: 8964

Synonyms: AMG-403 | JNJ-42160443
Compound class: Antibody
Comment: Fulranumab was an investigational, fully human IgG2κ monoclonal antibody targeting nerve growth factor (NGF) [1,6].
Peptide sequence information for this antibody is available from its IMGT/mAb-DB record.
BLAST peptide sequence analysis reveals identical matches to peptide sequences submitted with patent US7601818 [9], which belong to antibody clone 4D4 therein.
Selectivity at ligand targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
NGF Primary target of this compound Hs Antibody Binding 11.4 pKd - 9
⤷ pKd 11.4 (Kd 4x10-12 M) [9]