Ligand id: 8944

Name: emactuzumab

Compound class Antibody
International Nonproprietary Names
INN number INN
9951 emactuzumab
RG7155 | RO5509554
Emactuzumab is a humanized, IgG1κ anti-colony stimulating factor 1 receptor (CSF1R) monoclonal antibody, being investigated for its anti-cancer potential.
Peptide sequence and structural information for this antibody are available from its IMGT/mAb-db record.
Peptide sequence analysis using the heavy and light chain variable regions of emactuzumab reveals 100% matches to sequences 39 and 40 respectively from patent US20110165156 [1]. These two sequences belong to the clone named hMab 2F11-e7 (or simply 2F11) in the patent document.
Database Links
Specialist databases
IMGT/mAb-DB 501
Other databases
GtoPdb PubChem SID 310264725
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