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tezepelumab   Click here for help

GtoPdb Ligand ID: 8933

Synonyms: AMG 157 | AMG-157 | MEDI-9929 | MEDI9929 | tezepelumab-ekko | Tezspire®
Approved drug Immunopharmacology Ligand
tezepelumab is an approved drug
Compound class: Antibody
Comment: Tezepelumab is a fully human IgG2λ monoclonal antibody, that is a potential first-in-class agent that blocks the epithelial-cell-derived cytokine thymic stromal lymphopoietin (TSLP- which is an upstream modulator of multiple inflammatory pathways). It is being investigated for its immunomodulatory action.
Classification Click here for help
Compound class Antibody
Approved drug? Yes. EU EMA (2022)  |  US FDA (2021)
International Nonproprietary Names Click here for help
INN number INN
10172 tezepelumab
Synonyms Click here for help
AMG 157 | AMG-157 | MEDI-9929 | MEDI9929 | tezepelumab-ekko | Tezspire®
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 573
Other databases
GtoPdb PubChem SID 310264714
Search PubMed clinical trials tezepelumab
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