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                                                                Synonyms: REGN-1033 | REGN1033 | SAR-391786 | SAR391786
                                 
                                                         
                            Compound class: 
                                                            Antibody
                                 
                                
                                    
                                        Comment: Trevogrumab is a fully human moncolonal antibody, being investigated for its potential to treat diseases/disorders which are ameliorated or improved by inhibition of myostatin (a.k.a. GDF8). 
                            
                            
                          
                                
                                    
                                
                          
                                   
                                   
                                  
                                    
                                    
                                    Peptide sequences and structural information for this antibody are available from its IMGT/mAb-DB record. BLAST peptide searches of patented peptide sequences reveals exact matches between the heavy chain variable region (HCVR) and the light chain variable region (LCVR) of trevogrumab with sequences 360 and 368 respectively, from patent US8840894 B2 [3].  | 
                                    
Classification ![]()  | 
                                                    |
| Compound class | Antibody | 
International Nonproprietary Names ![]()  | 
                                                        |
| INN number | INN | 
| 10087 | trevogrumab | 
Synonyms ![]()  | 
                                                        
| REGN-1033 | REGN1033 | SAR-391786 | SAR391786 | 
Database Links ![]()  | 
                                                        |
| Specialist databases | |
| IMGT/mAb-DB | 556 | 
| Other databases | |
| GtoPdb PubChem SID | 310264710 | 
| Search PubMed clinical trials | trevogrumab | 
| Search PubMed titles | trevogrumab | 
| Search PubMed titles/abstracts | trevogrumab |