dapoxetine   Click here for help

GtoPdb Ligand ID: 7901

Synonyms: LY 210448 | LY-210448
Approved drug
dapoxetine is an approved drug (UK (2008))
Compound class: Synthetic organic
Comment: Dapoxetine hydrochloride (PubChem CID 71352) is the component used in marketed formulations.
Click here for help
IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: dapoxetine

2D Structure
Click here for help
Click here for structure editor
Physico-chemical Properties
Click here for help
Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 6
Topological polar surface area 12.47
Molecular weight 305.18
XLogP 5.23
No. Lipinski's rules broken 1
Click here for help
Canonical SMILES CN(C(c1ccccc1)CCOc1cccc2c1cccc2)C
Isomeric SMILES CN([C@H](c1ccccc1)CCOc1cccc2c1cccc2)C
InChI InChI=1S/C21H23NO/c1-22(2)20(18-10-4-3-5-11-18)15-16-23-21-14-8-12-17-9-6-7-13-19(17)21/h3-14,20H,15-16H2,1-2H3/t20-/m0/s1
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (UK (2008))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
6834 dapoxetine
Synonyms Click here for help
LY 210448 | LY-210448
Database Links Click here for help
CAS Registry No. 119356-77-3
ChEMBL Ligand CHEMBL2110900
DrugBank Ligand DB04884
DrugCentral Ligand 4381
GtoPdb PubChem SID 249565584
PubChem CID 71353
Search Google for chemical match using the InChIKey USRHYDPUVLEVMC-FQEVSTJZSA-N
Search Google for chemicals with the same backbone USRHYDPUVLEVMC
Search PubMed clinical trials dapoxetine
Search PubMed titles dapoxetine
Search PubMed titles/abstracts dapoxetine
UniChem Compound Search for chemical match using the InChIKey USRHYDPUVLEVMC-FQEVSTJZSA-N
UniChem Connectivity Search for chemical match using the InChIKey USRHYDPUVLEVMC-FQEVSTJZSA-N
Wikipedia Dapoxetine