famitinib

Ligand id: 7886

Name: famitinib

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 68.44
Molecular weight 410.21
XLogP 2.59
No. Lipinski's rules broken 0

Molecular properties generated using the CDK
Classification
Compound class Synthetic organic
IUPAC Name
5-(2-diethylaminoethyl)-2-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-3-methyl-6,7-dihydro-1H-pyrrolo[4,5-c]pyridin-4-one
Synonyms
compound 9 [PMID: 21028894] | SHR 1020 | SHR-1020 | SHR1020
Comments
Famitinib is a multi-targeted receptor tyrosine kinase inhibitor [1]. The compound is a structural analogue of sunitinib.
Famitinib is a 'pseudo' INN, that takes the form of an INN for a kinase inhibitor, but has not been submitted to the World Health Organisation for ratification.
Database Links
CAS Registry No. 945380-27-8
ChEMBL Ligand CHEMBL1278146
GtoPdb PubChem SID 249565577
PubChem CID 16662431
Search Google for chemical match using the InChIKey GKEYKDOLBLYGRB-LGMDPLHJSA-N
Search Google for chemicals with the same backbone GKEYKDOLBLYGRB
Search UniChem for chemical match using the InChIKey GKEYKDOLBLYGRB-LGMDPLHJSA-N
Search UniChem for chemicals with the same backbone GKEYKDOLBLYGRB