vardenafil   Click here for help

GtoPdb Ligand ID: 7320

Synonyms: Levitra® | Vivanza®
Approved drug PDB Ligand
vardenafil is an approved drug (EMA and FDA (2003))
Compound class: Synthetic organic
Comment: Vardenafil is a phosphodiesterase type 5 (PDE5A) inhibitor. Marketed formulations may contain vardenafil hydrochloride (PubChem CID 10142962).
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 121.28
Molecular weight 488.22
XLogP 4.2
No. Lipinski's rules broken 0
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Canonical SMILES CCOc1ccc(cc1c1nc(=O)c2n([nH]1)c(CCC)nc2C)S(=O)(=O)N1CCN(CC1)CC
Isomeric SMILES CCOc1ccc(cc1c1nc(=O)c2n([nH]1)c(CCC)nc2C)S(=O)(=O)N1CCN(CC1)CC
InChI InChI=1S/C23H32N6O4S/c1-5-8-20-24-16(4)21-23(30)25-22(26-29(20)21)18-15-17(9-10-19(18)33-7-3)34(31,32)28-13-11-27(6-2)12-14-28/h9-10,15H,5-8,11-14H2,1-4H3,(H,25,26,30)
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (EMA and FDA (2003))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
7950 vardenafil
Synonyms Click here for help
Levitra® | Vivanza®
Database Links Click here for help
CAS Registry No. 224785-90-4
ChEMBL Ligand CHEMBL1520
DrugBank Ligand DB00862
DrugCentral Ligand 2809
GtoPdb PubChem SID 178103893
PubChem CID 135400189
Search Google for chemical match using the InChIKey SECKRCOLJRRGGV-UHFFFAOYSA-N
Search Google for chemicals with the same backbone SECKRCOLJRRGGV
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SynPHARM 79463 (in complex with phosphodiesterase 5A)
UniChem Compound Search for chemical match using the InChIKey SECKRCOLJRRGGV-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey SECKRCOLJRRGGV-UHFFFAOYSA-N
Wikipedia vardenafil