Ligand id: 5072

Name: TL6

Species: Human

Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Tumor necrosis factor superfamily ligands
activation-inducible TNF-related ligand | glucocorticoid- induced TNF-related ligand
TL6 (official name, tumor necrosis factor ligand superfamily member 18) is a cytokine belonging to the tumor necrosis factor (TNF) ligand family. It is thought to be involved in T cell interactions with endothelial cells, via binding to its receptor TNFRSF18 (a.k.a. AITR and GITR).
Gene symbol Gene name Species Precursor protein name Synonyms
TNFSF18 TNF superfamily member 18 Human prepro-tumor necrosis factor ligand superfamily member 18 AITRL, hGITRL, TL6, tumor necrosis factor (ligand) superfamily, member 18, tumor necrosis factor superfamily member 18
Database Links
Ensembl Gene ENSG00000120337 (Hs)
GtoPdb PubChem SID 178101765
Human Protein Atlas ENSG00000120337 (Hs)
UniProtKB Q9UNG2 (Hs)
Wikipedia TNFSF18