RANK ligand

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Ligands
RANK ligand (Human)

GtoPdb Ligand ID: 5066

Synonyms: receptor activator of nuclear factor κB ligand | osteoclast differentiation factor (ODF) | osteoprotegerin ligand | TNFSF11

Compound class: Endogenous peptide in human, mouse or rat

Comment: RANK ligand (TNFSF11) is a member of the tumor necrosis factor (TNF) cytokine family. It can exist in both membrane-bound and soluble forms. It is a key factor for osteoclast differentiation and activation. Osteoprotegerin acts as a decoy receptor for RANK ligand.

Species: Human

Summary
Biological activity
References
Structure
Immunopharmacology

Immunopharmacology Comments
RANK ligand acts as a dentritic cell survival factor and is involved in regulation of the T cell-dependent immune response.

Immunopharmacology Comments

RANK ligand acts as a dentritic cell survival factor and is involved in regulation of the T cell-dependent immune response.