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TGFβ3   Click here for help

GtoPdb Ligand ID: 5062

Synonyms: TGF-beta-3 | transforming growth factor beta-3
Compound class: Endogenous peptide in human, mouse or rat
Species: Human
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
Natural/Endogenous Targets
Target
Transforming growth factor β receptor
transforming growth factor beta receptor 2
Selectivity at catalytic receptors
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
transforming growth factor beta receptor 2 Ligand is endogenous in the given species Hs Agonist Agonist 6.5 pKd - 2
⤷ pKd 6.5 (Kd 2.94x10-7 M) [2]
Description: Using a SPR assay and immobilised ligand.
Transforming growth factor β receptor Ligand is endogenous in the given species Hs Agonist Agonist - - -
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Other ligands which bind to or alter the activity of this ligand
Key to terms and symbols Click column headers to sort
Ligand Sp. Type Action Value Parameter Concentration range (M) Reference
retlirafusp alfa Peptide Approved drug Hs Fusion protein Binding - - - 1,3
⤷ [1,3]