FGF-1

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Ligands
FGF-1 (Human)

GtoPdb Ligand ID: 4923

Synonyms: acidic fibroblast growth factor | beta-endothelial cell growth factor | heparin-binding growth factor 1 (HBGF-1)

Compound class: Endogenous peptide in human, mouse or rat

Comment: Monomer and homodimer

Species: Human

Summary
Biological activity
References
Structure

References
1. Harding TC, Long L, Palencia S, Zhang H, Sadra A, Hestir K, Patil N, Levin A, Hsu AW, Charych D et al.. (2013) Blockade of nonhormonal fibroblast growth factors by FP-1039 inhibits growth of multiple types of cancer. Sci Transl Med, 5 (178): 178ra39. [PMID:23536011]
2. Ornitz DM, Xu J, Colvin JS, McEwen DG, MacArthur CA, Coulier F, Gao G, Goldfarb M. (1996) Receptor specificity of the fibroblast growth factor family. J Biol Chem, 271 (25): 15292-7. [PMID:8663044]

References

1. Harding TC, Long L, Palencia S, Zhang H, Sadra A, Hestir K, Patil N, Levin A, Hsu AW, Charych D et al.. (2013)
Blockade of nonhormonal fibroblast growth factors by FP-1039 inhibits growth of multiple types of cancer.
Sci Transl Med, 5 (178): 178ra39. [PMID:23536011]

2. Ornitz DM, Xu J, Colvin JS, McEwen DG, MacArthur CA, Coulier F, Gao G, Goldfarb M. (1996)
Receptor specificity of the fibroblast growth factor family.
J Biol Chem, 271 (25): 15292-7. [PMID:8663044]