Natural/Endogenous Targets
Target Guanylyl cyclase-A

Selectivity at catalytic receptors
Key to terms and symbols		Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference Guanylyl cyclase-A Hs Agonist Binding - - - 1 ⤷ [1]

Additional information and targets (data relate to human unless otherwise stated)
Description	Data	Reference
Potency order at Guanylyl cyclase-A	atrial natriuretic peptide (NPPA, P01160) ≥ brain natriuretic peptide (NPPB, P16860) >> C-type natriuretic peptide (NPPC, P23582)	2
Potency order at Guanylyl cyclase-B	C-type natriuretic peptide (NPPC, P23582) >> atrial natriuretic peptide (NPPA, P01160) >> brain natriuretic peptide (NPPB, P16860)	2
Potency order at natriuretic peptide receptor 3	atrial natriuretic peptide (NPPA, P01160) > C-type natriuretic peptide (NPPC, P23582) ≥ brain natriuretic peptide (NPPB, P16860)	2