succinylcholine   Click here for help

GtoPdb Ligand ID: 4004

Synonyms: Quelicin® | suxamethonium
Approved drug PDB Ligand
succinylcholine is an approved drug (FDA (1952))
Compound class: Synthetic organic
Comment: Succinylcholine (sux) is a short-acting depolarizing neuromuscular blocker. It acts as an acetylcholine agonist at nicotinic acetylcholine receptors at neuromuscular junctions, resulting in persistent depolarization of the motor end plate.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 11
Topological polar surface area 52.6
Molecular weight 290.22
XLogP -0.74
No. Lipinski's rules broken 1
SMILES / InChI / InChIKey
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Canonical SMILES O=C(OCC[N+](C)(C)C)CCC(=O)OCC[N+](C)(C)C
Isomeric SMILES O=C(OCC[N+](C)(C)C)CCC(=O)OCC[N+](C)(C)C
InChI InChI=1S/C14H30N2O4/c1-15(2,3)9-11-19-13(17)7-8-14(18)20-12-10-16(4,5)6/h7-12H2,1-6H3/q+2
InChI Key AXOIZCJOOAYSMI-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1952))
WHO Essential Medicine WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.
IUPAC Name Click here for help
trimethyl[2-({4-oxo-4-[2-(trimethylazaniumyl)ethoxy]butanoyl}oxy)ethyl]azanium
International Nonproprietary Names Click here for help
INN number INN
26 suxamethonium chloride
Synonyms Click here for help
Quelicin® | suxamethonium
Database Links Click here for help
CAS Registry No. 306-40-1 (source: Scifinder)
ChEMBL Ligand CHEMBL703
DrugBank Ligand DB00202
DrugCentral Ligand 2489
GtoPdb PubChem SID 178100830
PubChem CID 5314
RCSB PDB Ligand SCK
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Wikipedia Suxamethonium_chloride