Is a component of

relaxin

Peptide Sequence

XLYSALANKCCHVGCTKRSLARFC

pGlu-Leu-Tyr-Ser-Ala-Leu-Ala-Asn-Lys-Cys-Cys-His-Val-Gly-Cys-Thr-Lys-Arg-Ser-Leu-Ala-Arg-Phe-Cys

Post-translational Modification

The N-terminal glutamine is cyclised into pyroglutamate (pGlu/X). Fully active H2 relaxin is a heterodimer of the B chain and the A chain linked by two disulfide bonds, the first between B chain (residue 35) and A chain (residue 172), and the second between B chain (residue 47) and A chain (residue 185).