fluphenazine   Click here for help

GtoPdb Ligand ID: 204

Synonyms: Prolixin®
Approved drug
fluphenazine is an approved drug (FDA (1959))
Compound class: Synthetic organic
Comment: Fluphenazine belongs to the family of phenothiazine anti-psychotic drugs.
Click here for help
2D Structure
Click here for help
Click here for structure editor
Physico-chemical Properties
Click here for help
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 55.25
Molecular weight 437.17
XLogP 4.16
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
Click here for help
Canonical SMILES OCCN1CCN(CC1)CCCN1c2ccccc2Sc2c1cc(cc2)C(F)(F)F
Isomeric SMILES OCCN1CCN(CC1)CCCN1c2ccccc2Sc2c1cc(cc2)C(F)(F)F
InChI InChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2
InChI Key PLDUPXSUYLZYBN-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1959))
WHO Essential Medicine WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.
IUPAC Name Click here for help
2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol
International Nonproprietary Names Click here for help
INN number INN
946 fluphenazine
Synonyms Click here for help
Prolixin®
Database Links Click here for help
BindingDB Ligand 50017655
CAS Registry No. 69-23-8 (source: DrugBank)
ChEBI CHEBI:136842
ChEMBL Ligand CHEMBL726
DrugBank Ligand DB00623
DrugCentral Ligand 1212
GtoPdb PubChem SID 135650275
PubChem CID 3372
Search Google for chemical match using the InChIKey PLDUPXSUYLZYBN-UHFFFAOYSA-N
Search Google for chemicals with the same backbone PLDUPXSUYLZYBN
Search PubMed clinical trials fluphenazine
Search PubMed titles fluphenazine
Search PubMed titles/abstracts fluphenazine
Search UniChem for chemical match using the InChIKey PLDUPXSUYLZYBN-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone PLDUPXSUYLZYBN
Wikipedia Fluphenazine