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zumilokibart   Click here for help

GtoPdb Ligand ID: 14544

Synonyms: APG-777 | APG777
Immunopharmacology Ligand
Compound class: Antibody
Comment: Zumilokibart (APG-777) is an interleukin 13 (IL-13) neutralising monoclonal antibody [1,3]. It is engineered to have an extended circulating half-life [2].
No information available.
Summary of Clinical Use Click here for help
Zumilokibart (APG-777) was progressed as a clinical candidate for the treatment of inflammatory diseases that are characterised by Type 2 inflammation, initially targeting atopic dermatitis, and with intentions to expand into eosinophilic esophagitis and asthma.
Clinical Trials
Clinical Trial ID Title Type Source Comment References
NCT06395948 A Study Evaluating APG777 in Atopic Dermatitis Phase 2 Interventional Apogee Therapeutics, Inc.
NCT07003425 A Long-term Safety and Efficacy Study Evaluating APG777 in Atopic Dermatitis Phase 2 Interventional Apogee Therapeutics, Inc.