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duvakitug   Click here for help

GtoPdb Ligand ID: 14420

Synonyms: TEV-48574 | TEV48574
Immunopharmacology Ligand
Compound class: Antibody
Comment: Duvakitug (TEV-48574) is a fully human IgG1λ monoclonal antibody that targets TL1A (TNFSF15) [6]. TL1A signalling through its receptor, death receptor 3 (DR3) modulates inflammatory responses and is implicated in profibrotic pathways [1,3-4]. Based on amino acid sequence matches to the heavy and light chain variable regions of duvakitug we suspect this is antibody clone 320-587 in patent US10138296B2 [5].
Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
12561 duvakitug
Synonyms Click here for help
TEV-48574 | TEV48574
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 1396
Other databases
Search PubMed clinical trials duvakitug
Search PubMed titles duvakitug
Search PubMed titles/abstracts duvakitug