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suvemcitug   Click here for help

GtoPdb Ligand ID: 14397

Synonyms: BD-0801 | BD0801 | Enzeshu® (China)
Approved drug
suvemcitug is an approved drug
Compound class: Antibody
Comment: Suvemcitug (BD0801) is a humanized anti-VEGFA monoclonal antibody that was designed for anti-tumour action [1].
Bioactivity Comments
Binds to VEGFA165 with affinity (Kd) of 0.012 nM and to VEGFA164 with similar affinity [1]. In contrast bevacizumab does not bind to VEGFA164.
Selectivity at ligand targets
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
VEGFA Hs Antibody Binding 10.9 pKd - 1
⤷ pKd 10.9 (Kd 1.2x10-11 M) [1]
Description: Affinity for VEGFA165