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etigilimab   Click here for help

GtoPdb Ligand ID: 13984

Synonyms: OMP-313M32
Immunopharmacology Ligand
Compound class: Antibody
Comment: Etigilimab (OMP-313M32) is an anti-TIGIT monoclonal antibody [1]. Blocking the TIGIT/PVR interaction is proposed to promote anti-tumour immunity. This mechanism is proposed to be used in conjunction with anti-PD/1/PD-L1 immuno-oncology therapeutics, to further enhance the anti-tumour immune response.
Selectivity at other protein targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
TIGIT Hs Antibody Binding - - - 2
⤷ [2]