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seniprutug   Click here for help

GtoPdb Ligand ID: 13939

Synonyms: BCD-180 | BCD180
Approved drug Immunopharmacology Ligand
seniprutug is an approved drug
Compound class: Antibody
Comment: Seniprutug (BCD-180) is a monoclonal antibody that targets T cell receptor beta variable 9 (TRBV9) [1]. It induces antibody-dependent cellular cytotoxicity in the target effector T cell population without causing risk of systemic immunosuppression (that would be caused by destroying T cell subsets that are responsible for essential protective functions).
Bioactivity Comments
We have been unable to find quantitative data to support interaction of this antibody with its proposed molecular target (June 2025).