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quavonlimab   Click here for help

GtoPdb Ligand ID: 13890

Synonyms: MK-1308 | MK1308
Immunopharmacology Ligand
Compound class: Antibody
Comment: Quavonlimab (MK-1308) is a humanized IgG1 anti-CTLA-4 monoclonal antibody [1]. It blocks the inhibitory CTLA-4/CD80/CD86 immune checkpoint, as a mechanism to reactivate anti-tumour immune surveillance.
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
11234 quavonlimab
Synonyms Click here for help
MK-1308 | MK1308
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 1024
Other databases
GtoPdb PubChem SID 513757575
Search PubMed clinical trials quavonlimab
Search PubMed titles quavonlimab
Search PubMed titles/abstracts quavonlimab