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Synonyms: AK-101 | AK101
ebdarokimab is an approved drug
Compound class:
Antibody
Comment: Ebdarokimab (AK101) is a humanized IgG1-κ, dual IL-12/IL-23 targeting monoclonal antibody. It binds to the common p40 subunit (IL12B) of these cytokines and disrupts pro-inflammatory signalling via their receptors on T cells and natural killer (NK) cells.
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Classification ![]() |
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Compound class | Antibody |
Approved drug? | Yes. China NMPA (2025) |
International Nonproprietary Names ![]() |
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INN number | INN |
11582 | ebdarokimab |
Synonyms ![]() |
AK-101 | AK101 |
Database Links ![]() |
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Specialist databases | |
IMGT/mAb-DB | 1126 |
Other databases | |
GtoPdb PubChem SID | 513757560 |
Search PubMed clinical trials | ebdarokimab |
Search PubMed titles | ebdarokimab |
Search PubMed titles/abstracts | ebdarokimab |