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ebdarokimab   Click here for help

GtoPdb Ligand ID: 13875

Synonyms: AK-101 | AK101
Approved drug Immunopharmacology Ligand
ebdarokimab is an approved drug
Compound class: Antibody
Comment: Ebdarokimab (AK101) is a humanized IgG1-κ, dual IL-12/IL-23 targeting monoclonal antibody. It binds to the common p40 subunit (IL12B) of these cytokines and disrupts pro-inflammatory signalling via their receptors on T cells and natural killer (NK) cells.
Selectivity at ligand targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
IL-12B Hs Antibody Binding - - -
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