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interleukin 18 binding protein   Click here for help

GtoPdb Ligand ID: 13868

Immunopharmacology Ligand
Compound class: Endogenous peptide in human, mouse or rat
Comment: Interleukin 18 binding protein (IL18BP) binds to and inhibits the activity of circulating pro-inflammatory IL-18 at its receptor [3].
Synthetic IL18BP mimetics offer potential anti-inflammatory action for the treatment of inflammation-mediated (and autoimmune) diseases [1-2].
Species: Human
Selectivity at ligand targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
IL-18 Hs None Binding - - - 3
⤷ [3]