xeligekimab

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xeligekimab

GtoPdb Ligand ID: 13784

Synonyms: GR-1501 | GR1501

xeligekimab is an approved drug

Compound class: Antibody

Comment: Xeligekimab (GR1501) is a human IgG4 monoclonal antibody that targets IL-17A [2].

Summary
Biological activity
Clinical data
References
Immunopharmacology

References
1. Blair HA. (2025) Xeligekimab: First Approval. Drugs, 85 (1): 97-101. [PMID:39702866]
2. Shan Y, Shi K, Qian X, Chang Z, Yang J, Gao Y, Jin W, Luo Q, Xu Q. (2019) Preclinical development of GR1501, a human monoclonal antibody that neutralizes interleukin-17A. Biochem Biophys Res Commun, 517 (2): 303-309. [PMID:31353088]

References

1. Blair HA. (2025)
Xeligekimab: First Approval.
Drugs, 85 (1): 97-101. [PMID:39702866]

2. Shan Y, Shi K, Qian X, Chang Z, Yang J, Gao Y, Jin W, Luo Q, Xu Q. (2019)
Preclinical development of GR1501, a human monoclonal antibody that neutralizes interleukin-17A.
Biochem Biophys Res Commun, 517 (2): 303-309. [PMID:31353088]