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ponsegromab   Click here for help

GtoPdb Ligand ID: 13663

Synonyms: PF-06946860 | PF06946860
Compound class: Antibody
Comment: Ponsegromab (PF-06946860) is a humanized monoclonal antibody that binds and neutralises the action of the GDF-15 cytokine. It was designed to inhibit aberrant GDF-15/GDNF family receptor alpha like (GFRAL)-mediated dysregulation of appetite in human diseases, particularly in cancer patients.
Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
11605 ponsegromab
Synonyms Click here for help
PF-06946860 | PF06946860
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 1141
Other databases
CAS Registry No. 2368950-15-4 (source: WHO INN record)
GtoPdb PubChem SID 507750297
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